ResumePei-Sen Yao
Address:
NO. 20 Changzhong Road, Fuzhou City, 350004, China
Cell phone:
(+86)13959790518
Email: peisen.yao@163.com
Appointments
Date
2010-2011
2014-present
Institution
Department of neuro-intensive care unit, the second affiliated hospital of Fujian Medical University
Department of neurosurgery, the first affiliated hospital of Fujian Medical University
Title
Resident doctor
Resident doctor
Education
Education
Undergraduate
Graduate
Post-Graduate
 
Date
2003-2008
2008-2010
2011-2014
 
Institution
Fujian Medical University
Fujian Medical University
Fujian Medical University
 
Degree
M.B. 2008
M.S. 2010
M.D. Ph.D. 2014
 
Advisor & Major
Clinical Medicine
De-Zhi Kang Neurosurgery
De-Zhi Kang and Zu-Cheng Ye
Neurosurgery and Neuroscience
Training/ Experience
Date
2009-2010
2010-2011
2011-2014
2011-2014
Institution
Department of neurosurgery, the first affiliated hospital of Fujian Medical University
The second affiliated hospital of Fujian Medical University
Center for neuroscience, Fujian Medical University
Center for neuroscience, Fujian Medical University
Title
Intraoperative neurophysiological monitoring
Surgical techniques
Methods in Molecular Biology
Establishing human gliosarcoma cell line (K308) and glioblastoma cell lines (YD307 and YD309)
Research
Source:
Title:
Role on Project:
Specific Aims:
Source:
Title:
Role on Project:
Specific Aims:
National Natural Science Foundation of China (NSFC), No. 31271153
Glutamine-glutamate cycling between glioma cells and astrocytes: mechanism and the impact of the resulting oxidative stress.
Principal Investigator
This grant investigates the potential counteractions from normal astrocytes against glioma glutamate release
National Natural Science Foundation of China (NSFC), No. 81372345
Selection of aptamers from glioma stem cells.
Principal Investigator
This grant investigates the potential aptamers in the detection of glioma stem cells from glioma samples.
List of current research/clinical interests
1. Cognitive dysfunction in patients with glioma
2. Intraoperative neurophysiological monitoring
3. Induced differentiation of glioma stem cells
4. Glutamatic metabolism of gliomas
5. Surgery on intracranial aneurysms via keyhole approaches
6. Extended Resection combining with function preservation on intracranial glioma
Personal services and activities
1. Membership of society for neuroscience (USA), 2013
2. Invited speaker for annual meeting of society for neuroscience, San Diego, CA, 2013
3.Editorial member and reviewer of International Journal of Advances in Neurology and Neurological Disorder Research (IJANNDR).
Welcome to submit articles to IJANNDR (http://www.djneuro.org/).
Journal papers
1. Kang DZ, Yao PS, Wu ZY, Yu LH. Ischemia changes and tolerance ratio of evoked potential monitoring in intracranial aneurysm surgery. Clin Neurol Neurosurg 2013; 115(5): 552-6.

View Full Text.
http://pan.baidu.com/share/link?shareid=1317342773&uk=69792484

2. Yao PS, Kang DZ, Lin RY, Ye B, Wang W, Ye ZC. Glutamate/glutamine metabolism coupling between astrocytes and glioma cells: Neuroprotection and inhibition of glioma growth. Biochem Biophys Res Commun 2014; 450(1): 295-9.

View Full Text.
http://pan.baidu.com/share/link?shareid=1320614423&uk=69792484

3. Wang DL, Song YL, Zhu Z, Li XL, Zou Y, Yang HT, Wang JJ, Pan RJ, Yao PS, Yang CJ, Kang DZ. Selection of DNA aptamers against epidermal growth factor receptor with high affinity and specificity. Biochem Biophys Res Commun 2014; 453(4): 681-5.

View Full Text
http://pan.baidu.com/share/link?shareid=1322409462&uk=69792484

4. Yao PS, Kang DZ, Wang XF, Lin RY, Ye ZC. Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line. In vitro cellular & developmental biology Animal 2015; 51(4): 345-52.

View Full Text
http://pan.baidu.com/share/link?shareid=1324558272&uk=69792484

5. Liang-Hong Yu, Pei-Sen Yao, Shu-Fa Zheng, De-Zhi Kang. Retractorless surgery for anterior circulation aneurysms via pterional keyhole approach. World neurosurgery (2015), doi: 10.1016/ j.wneu.2015.07.055.

View Full Text
http://pan.baidu.com/share/link?shareid=1326338892&uk=69792484



Open link for Video 1 (Retractorless surgery for ACA aneurysm).
1) http://pan.baidu.com/share/link?shareid=1330128437&uk=69792484
2) http://www.sciencedirect.com/science/article/pii/S1878875015009250

Open link for Video 2 (Retractorless surgery for MCA aneurysm).
1) http://pan.baidu.com/share/link?shareid=1331690635&uk=69792484
2) http://www.sciencedirect.com/science/article/pii/S1878875015009250

6. Shu-Fa Zheng, Pei-Sen Yao, Liang-Hong Yu, De-Zhi Kang. Anterior interhemispheric keyhole approach for treatment of aneurysms at the A3 segment of anterior cerebral artery: preliminary experience in 13 patients. Turkish neurosurgery 2015 (accepted).
7. Shu-Fa Zheng, Pei-Sen Yao, Liang-Hong Yu, De-Zhi Kang. Keyhole approach combined with external ventricular drainage for ruptured, poor-grade, anterior circulation cerebral aneurysms. Medicine 2015 (accepted).

View Full Text
http://pan.baidu.com/share/link?shareid=1336428494&uk=69792484

Conference papers
1. Yao PS, Kang DZ, Lin RY, Wang W, Ye ZC. Determination of extracellular glutamate concentration in mixed culture of astrocytes and glioma cells. Soc Neurosc Abstr Viewer Itiner Plan 2013; 43.
Personal
Native speaker of Chinese, fluent in English. Enjoy table tennis, fishing and calligraphy.